1974

• Japan Clinic Co., Ltd. commences operations with the sale of “Kaki” Tablets.
• Establishment of the Sendai Regional Sales Office.

1976

• Establishment of the Hiroshima and Sapporo Regional Sales Offices.

1978

• Establishment of the Food and Nutrition Counseling Office, offering after-sales services to our consumers.
• Signing of a business partnership with Mitsubishi Shokuhin Co., Ltd. (a subsidiary of Mitsubishi Corporation), resulting in the distribution of “Kaki” Tablets to pharmacies across Japan.

1979

• Signing of a business partnership with Sumitomo Corporation, resulting in the distribution of “Sea Milk” Tablets to pharmacies across Japan.

1981

• Completion of the Japan Clinic Head Office Building in Kyoto City.
• Establishment of the Tokyo Regional Sales Office.

1983

• Commences sale of the “Kaki” Drink.
• Establishment of the Central Research Center.

1984

• Construction of the Miyazu Factory complete.
• Foundation of the Japan Trace Nutrients Research Society, setting in motion a long history of joint studies with Universities in Japan, France, and the USA.

1985

• Successful isolation of Z-Substance from Oyster Extract, leading to the development of “Balanceter–Z”, an improved formula fortified with Z-Substance.
• Establishment of the Fukuoka Regional Sales Office.

1986

• Signing of a business partnership with the Japanese Liquor Merchants Cooperative Association, resulting in the distribution of Oyster Extract products liquor stores across Japan.

1991

• Establishment of the Nagoya Regional Sales Office.

1993

• Establishment of the Kansai Regional Sales Office.
• Obtains a patent in relation to a substance with platelet aggregation inhibiting properties. (Patent Number: 1770901 Japan)

1994

• Obtains a patent in relation to a substance with platelet aggregation inhibiting properties. (Patent Number: 1813693 Japan)
• Japan Clinic’s 20th Anniversary Ceremony held at Kyoto International Conference Center.
• Establishment of the JCOE Research Society organized by pharmacies from across Japan.

1995

• Obtains a patent in relation to a substance with brain lithium concentration augmentative properties. (Patent Number: 1906437 Japan)
• Obtains a patent in relation to a substance applicable to the treatment of schizophrenia. (Patent Number: 1932241 Japan)

1996

• Obtains patents in relation to substances with platelet aggregation inhibiting properties. (Patent Number: 2007451, 2007452 Japan)

1997

• Obtains a patent for the isolation of a low-molecular weight fraction of Oyster Extract. (Patent Number: 2129831 Japan)

1999

• Obtains a patent in relation to a substance with anti-oxidant properties and its production method. (Patent Number: 5925382 USA)

2000

• Hosts the first Annual JCOE Regional Administrator’s Assembly at the Miyako Hotel in Kyoto City.

2001

• Commences sale of the “Balanceter-WZ” Tablets. An Oyster Extract Tablet fortified with the FC-Substance.

2002

• “Balanceter–WZ” awarded the Lifestyle Reformation Award at the 2002 14th Topics Award sponsored by Drug Magazine Co., Ltd. and Yachiyo-Kai.
• Registration of the “Kaki-Niku Man” mascot character as Japan Clinic’s Trademark.
• Commences sale of the renewal formula version “Kaki 750 Drink” fortified with FC-Substance.
• Successful isolation of FC-Substance from Oyster Extract, leading to the obtainment of patents pertaining to the substance and its production method. (Patent Number: 3267962 Japan)

2003

• Signing of a trade agreement with a Hong Kong based company.
• Obtains patents pertaining to the FC-Substance and its production method, the W-Extraction Method. (Patent Number: 3429726 Japan)

  Equivalent Patents Obtained :

  2005(6884456, 6962723 USA)

  2006(783771 Australia)

2005

• Commences sale of the renewal package version “Kaki” Tablet.

2006

• Obtains a patent pertaining to the extraction method of pure taurine from Oyster Extract. (Patent Number: 3819000 Japan)
• Hosts the first National JCOE Convention at the Westin Miyako Hotel in Kyoto.
• “Kaki” awarded the Renewal Product Award at the 2006 18th Topics Award sponsored by Drug Magazine Co., Ltd. and Yachiyo-Kai.
• Obtains a patent pertaining to the extraction method of a copper rich fractionation from Oyster Extract. (Patent Number: 3853816 Japan)

2007

• Establishment of the Food and Nutrition Counseling Office’s web-shop.

2008

• Obtains a patent pertaining to the production of salt derived from Oysters. (Patent Number: 4087890 Japan)
• Obtains a patent pertaining to a substance with anti-oxidant properties and its production method. (Patent Number: 4121583 Japan)
• Expansion of the Japan Trace Nutrients Research Society, and the hosting of the 25th annual Japan Trace Nutrients Research Society Academic Forum.
• Commences sale of the “Half-Sitoal Drink” – Recognized by the Consumer Affairs Agency of Japan as a “Food for Specified Health Uses – aka Tokuho”.

2009

• Hosts the second National JCOE Convention at the Westin Miyako Hotel in Kyoto.
• Obtains a patent pertaining to Oyster Extract containing a water-soluble form of zinc. (Patent Number: 4328842 Japan)

2010

• Commences sale of the “Balanceter - 1550” Drink.

2011

• Obtains a patent pertaining to the production method of Oyster Extract. (Patent Number: 4703574 Japan)

2013

• Japan Trace Nutrient Research Society’s 30th Annual Symposium takes place in Kyoto City.

2014

• Hosts the third National JCOE Convention at the Westin Miyako Hotel in Kyoto.

2016

• Completion of the Miyazu Factory renovation project.
• Miyazu Factory granted GMP certification by the Japan Health and Nutrition Food Association.

2017

• Relocation of the Head Office to Taishogun District in North Ward of Kyoto City.
• “Balanceter–WZ” awarded the Healthy Lifestyle Essentials Award at the 2017 29th Topics Award sponsored by Drug Magazine Co., Ltd. and Yachiyo-Kai.